The effect of the anabolic agent, clenbuterol, on overloaded rat skeletal muscle.
نویسندگان
چکیده
The dietary administration of clenbuterol to young male rats has been shown to produce a muscle specific hypertrophic growth response. This paper demonstrates that the combined effect of drug treatment and hypertrophic stimulus induced by tenotomy produced an additive effect on muscle growth. This effect was demonstrated in terms of both muscle composition (protein and RNA) and fibre size.
منابع مشابه
2-Agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol
Ryall, James G., Paul Gregorevic, David R. Plant, Martin N. Sillence, and Gordon S. Lynch. 2-Agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol. Am J Physiol Regul Integr Comp Physiol 283: R1386–R1394, 2002. First published September 5, 2002; 10.1152/ajpregu.00324.2002.—Potential treatments for skeletal muscle wasting and weakness ideally poss...
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Clenbuterol is known to have therapeutic potential in ameliorating muscle atrophy because of its presumed anabolic effects. However, little is known about its effects on lipids under normal and stress conditions. Male rats of Wistar strain were shedied under work stress and clenbuterol treatment to understand the lipid status. Animals were subjected to work over load stress and then treated wit...
متن کاملBeta 2-agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol.
Potential treatments for skeletal muscle wasting and weakness ideally possess both anabolic and ergogenic properties. Although the beta(2)-adrenoceptor agonist clenbuterol has well-characterized effects on skeletal muscle, less is known about the therapeutic potential of the related beta(2)-adrenoceptor agonist fenoterol. We administered an equimolar dose of either clenbuterol or fenoterol to r...
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ورودعنوان ژورنال:
- Bioscience reports
دوره 7 2 شماره
صفحات -
تاریخ انتشار 1987